CNS Injuries

DEVELOPING STRATEGIES TO BRIDGE CNS DEFICITS

The annual incidence of traumatic brain injury (TBI) amounts to approximately 1.7 million new cases each year in The United States. Trauma to the CNS leads to irreversible neural damage and loss of function that can be devastating to a person’s quality of life. Unfortunately, the multifaceted nature of CNS trauma makes targeted therapeutic application difficult, and current strategies to bridge CNS deficits are limited in their ability to effectuate long-term repair, and facilitate functional recovery.  In efforts to address these limitations, we are developing multi-functional biomimetic glycomaterials for stem cell transplantation, and trophic factor enrichment after moderate TBI.

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