Journal Articles  |  Book Chapters


Glycosaminoglycan scaffolding and neural progenitor cell transplantation promotes regenerative immunomodulation in the mouse ischemic brain.
McCrary MR, Jiang MQ, Jesson K, Gu X, Logun MT, Wu A, Gonsalves N, Karumbaiah L, Yu SP, Wei L. Experimental Neurology. 357; 114177, 11/1/2022.

Synthetic Heparan Sulfate Hydrogels Regulate Neurotrophic Factor Signaling and Neuronal Network Activity.
Latchoumane C-FV, Chopra P, Sun L, Ahmed A, Palmieri F, Wu H-F, Guerreso R, Thorne K, Zeltner N, Boons G-J, Karumbaiah L. ACS Applied Materials & Interfaces. 14 (25) 28476-28488, 6/16/2022.

Glycomaterials to Investigate the Functional Role of Aberrant Glycosylation in Glioblastoma.
Tondepu.C, Karumbaiah.L. Advanced Healthcare Materials. (4):e2101956, 2022 Feb.


Cortical Laminar Recording of Multi-unit Response to Distal Forelimb Electrical Stimulation in Rats.
Latchoumane C-F.V, Forghani. R, Karumbaiah. L. Bio-Protocol. 11(22), pp.e4153-e4153., 2021 Nov.

Engineered glycomaterial implants orchestrate large-scale functional repair of brain tissue chronically after severe traumatic brain injury.
Latchoumane C-FV, Betancur MI, Simchick GA, Sun M, Forghani R, Lenear CE, Ahmed A, Mohankumar R, Balaji N, Mason HD, Archer-Hartmann SA, Azadi P, Holmes PV, Bellamkonda RV, Karumbaiah L* (Corresponding Author). Science Advances. eabe0207, Mar 2021.


Neurotrophic Factor-Laden Acellular Chondroitin Sulfate Scaffolds Promote Chronic Functional Recovery After Severe Traumatic Brain Injury.
Latchoumane C-FV, Betancur MI, Simchick GA, Sun MK, Forghani R, Lenear CE, Ahmed A, Mohankumar R, Balaji N, Mason HD, Holmes PV, Zhao Q, Bellamkonda RV, Karumbaiah L* (Corresponding Author). BioRxiv. 07, 2020 July.

Label-free ferrohydrodynamic separation of exosome-like nanoparticles.
Liu Y, Zhao W, Cheng R, Logun MT, Zayas-Viera MDM, Karumbaiah L, Mao L. Lab on a chip. 2020, 2020 July.

Cortical Transplantation of Brain-Mimetic Glycosaminoglycan Scaffolds and Neural Progenitor Cells Promotes Vascular Regeneration and Functional Recovery after Ischemic Stroke in Mice.
McCrary MR, Jesson K, Wei ZZ, Logun MT, Lenear C, Tan S, Gu X, Jiang MQ, Karumbaiah L, Yu SP, Wei L. Advanced Healthcare Materials. e1900285., Jan 2020.


Extracellular vesicles mediate neuroprotection and functional recovery after traumatic brain injury.
Sun MK, Passaro AP, Latchoumane C-F, Spellicy SE, Bowler M, Goeden M, Martin WJ, Holmes PV, Stice SL, Karumbaiah L* (Corresponding Author). Journal of Neurotrauma. neu.2019.6443, Nov 2019.

Surfen-mediated blockade of extratumoral chondroitin sulfate glycosaminoglycans inhibits glioblastoma invasion.
Logun. M.T, Wynens. K.E, Simchick. G, Zhao. W, Mao. L, Zhao. Q, Mukherjee. S, Brat. D.J, Karumbaiah. L* (Corresponding Author). FASEB Journal., Aug 2019.

A fully Synthetic Heparan Sulfate-Based Neural Tissue Construct that Maintains the Undifferentiated State of Neural Stem Cells.
Chopra.P, Logun. M.T, White. E.M, Lu W, Locklin. J, Karumbaiah. L*, Boons. G-J* (Co-Corresponding Authors). ACS Chemical Biology., Aug 2019.

Five-dimensional two-photon volumetric microscopy of in-vivo dynamic activities using liquid lens remote focusing.
Tehrani KF, Latchoumane C-F.V, Southern MW, Pendleton EG, Maslesa A, Karumbaiah L, Call JA, Mortensen LJ. Biomedical Optics Express. 10(7):3591-604, June 2019.

Expanding Hydrophobically Modified Chitosan Foam for Internal Surgical Hemostasis: SafetyEvaluation in a Murine Model.
Logun MT, Dowling MB, Raghavan SR, Wallace ML, Schmiedt C, Stice SL, Karumbaiah L* (Corresponding Author). Journal of Surgical Research. 239:269-277, 2019 Mar.

Chondroitin Sulfate Glycosaminoglycan Scaffolds for Cell and Recombinant Protein‐Based Bone Regeneration.
Andrews S, Cheng A, Stevens H, Logun MT, Webb R, Jordan E, Xia B, Karumbaiah L, Guldberg RE, Stice SL. Stem Cells Translational Medicine. 2019;00:1–11, 2019 Jan.


Engineering Controlled Peritumoral Inflammation to Constrain Brain Tumor Growth.
Saxena T, Lyon JG, Pai BS, Pare D, Amero J, Karumbaiah L, Carroll SL, Gaupp E, Bellamkonda RV. Advanced Healthcare Materials. 1801076, December 2018.

Chronic Electrical Stimulation Promotes the Excitability and Plasticity of ESC-derived Neurons following Glutamate-induced Inhibition In vitro.
Latchoumane C-F. V, Jackson L, Sendi M. S. E, Tehrani K. F, Mortensen L. J, Stice S. L, Ghovanloo M, Karumbaiah L* (Corresponding Author). Scientific Reports. 8:10957, July 2018.

Lesion Volume Estimation from TBI–MRI.
Sarma S. O. V, Betancur M. I, Pidaparti R, Karumbaiah L. Progress in Advanced Computing and Intelligent Engineering. 563: 197-207, Feb 2018.

Microfluidics in Malignant Glioma Research and Precision Medicine.
Logun MT, Zhao W, Mao L, Karumbaiah L * (Corresponding Author). Advanced biosystems. 1700221, April 2018.


Sustained Release of Transforming Growth Factor-β1 from Platelet-Rich CS-GAG Gels.
Birdwhistell KE, Karumbaiah L, Franklin SP. Journal of Knee Surgery. 30, May 2017.

Fast axial scanning for 2-photon microscopy using liquid lens technology.
Tehrani KF, Sun MK, Karumbaiah L, Mortensen LJ. SPIE Proceedings. 10070, 2017 March.

Chondroitin Sulfate Glycosaminoglycan Matrices Promote Neural Stem Cell Maintenance and Neuroprotection Post-Traumatic Brain Injury.
Betancur MI, Mason HD, Alvarado-Velez M, Holmes PV, Bellamkonda RV, and Karumbaiah L* (Corresponding Author). ACS Biomaterials Science and Engineering. 10.1021/acsbiomaterials.6b00805, 2017 Jan.


Glioma cell invasion is significantly enhanced in composite hydrogel matrices composed of chondroitin 4- and 4,6-sulfated glycosaminoglycans.
Logun MT, Bisel NS, Tanasse EA, Zhao W, Gunasekera B, Mao L, Karumbaiah L* (Corresponding Author). J. Mater. Chem. B. 4,6052-6064, 2016 Aug.


Extracellular matrix-based intracortical microelectrodes: Toward a microfabricated neural interface based on natural materials.
Shen W, Karumbaiah L, Liu X, Saxena T, Chen S, Patkar R, Bellamkonda RV, Allen MG. Microsystems & Nanoengineering. 15010 (2015), 2015 June.

Nanocarrier Mediated Inhibition of Macrophage Migration Inhibitory Factor Attenuates Secondary Injury after Spinal Cord Injury..
Saxena T, Loomis KH, Pai BS, Karumbaiah L, Gaupp E, Patil K, Patkar R, Bellamkonda RV. ACS Nano. 14,2015, 2015.

Intracortical Recording Interfaces: Current Challenges to Chronic Recording Function..
Gunasekera B, Saxena T, Bellamkonda R, Karumbaiah L* (Corresponding Author). ACS Chem Neurosci. 14, 2015, 2015.


Chondroitin Sulfate Glycosaminoglycans for CNS Homeostasis – Implications for Material Design..
Karumbaiah L* (Corresponding Author), Saxena T, Betancur M, Bellamkonda RV. Current Medicinal Chemistry. 21(37):4257-81, 2014.

Molecular Sequelae of Topographically Guided Peripheral Nerve Repair..
Mukhatyar V, Pai B, Clements I, Srinivasan A, Huber R, Mehta A, Mukhopadaya S, Rudra S, Patel G, Karumbaiah L, Bellamkonda R. Ann Biomed Eng. 42(7):1436-55, 2014 Jul.


Relationship between intracortical electrode design and chronic recording function..
Karumbaiah L, Saxena T, Patil K, Betancur M, Patkar R, Stanley GB, Bellamkonda RV. Biomaterials. 34(33):8061-74, 2013 Nov.

The Impact of Chronic Blood-Brain Barrier Breach on Intracortical Electrode Function.
Saxena T, Karumbaiah L*, Gaupp E, Patkar R, Patil K, Betancur M, Stanley GB, Bellamkonda RV. Biomaterials. 34(20):4703-13, 2013 Jul.

Prior to Joining UGA

The upregulation of specific interleukin (IL) receptor antagonists and paradoxical enhancement of neuronal apoptosis due to electrode induced strain and brain micromotion..
Karumbaiah L, Norman SE, Rajan NB, Anand S, Saxena T, Betancur M, Patkar, Bellamkonda RV. Biomaterials. 33(26):5983-96, 2012 Sep.

Anti-invasive adjuvant therapy with Imipramine Blue enhances chemotherapeutic efficacy against glioma.
Munson JM, Fried L, Rowson SA, Bonner MY, Karumbaiah L, Diaz B, Courtneidge SA, Knaus U, Brat DJ, Arbiser JL, Bellamkonda RV. Sci. Transl. Med.. 127ra36, 2012 Mar.

Photocrosslinkable Chitosan Based Hydrogels for Neural Tissue Engineering.
Valmikinathan CM, Mukhatyar VJ, Jain A, Karumbaiah L, Dasari M, Bellamkonda RV. Soft Matter. 8, 1964-1976, 2012.

Reduced Levels of Membrane-Bound Alkaline Phosphatase Are Common to Lepidopteran Strains Resistant to Cry Toxins from Bacillus thuringiensis.
Jurat-Fuentes JL, Karumbaiah L, Jakka SR, Ning C, Liu C, Wu K, Jackson J, Gould F, Blanco C, Portilla M, Perera O, Adang MJ. PLoS One. 6(3):e17606, 2011 Mar.

Evaluation of tumor microenvironment in an animal model using a nanoparticle contrast agent in computed tomography imaging.
Ghaghada KB, Badea CT, Karumbaiah L, Fettig N, Bellamkonda RV, Johnson GA, Annapragada A. Academic Radiology. 18(1):20-30, Jan 2011.

Tissue engineering strategies designed to facilitate the endogenous regenerative potential of peripheral nerves.
Mukhatyar V, Karumbaiah L, Yeh J, Bellamkonda RV. Adv Materials. 21(46); 4670-4679, 2009 Nov.

Tumor vascular permeability of a nanoprobe correlates to tumor-specific expression levels of angiogenic markers.
Karathanasis E, Chan L, Karumbaiah L, McNeeley K, D'Orsi C, Annapragada A, Sechopoulos I, Bellamkonda RV. PLoS One. 4(6):e5843, 2009 Jun.

Analysis of midgut proteinases from Bacillus thuringiensis-susceptible and resistant Heliothis virescens (Lepidoptera: Noctuidae).
Karumbaiah L, Oppert B, Jurat-Fuentes JL, Adang MJ. Comp Biochem Physiol B Biochem Mol Biol. 146(1):139-46, Jan 2007.

Book Chapters

Molecular and Extracellular Cues in Motor Neuron Specification and Differentiation.
Swetenburg, R.L.; Stice, S.L.; Karumbaiah, L. Molecular and Cellular Therapies for Motor Neuron Diseases. 1-24, 2017 Jan.

Advancing Chronic Intracortical Electrode Recording function, Advances In Real-Time Molecular Neuroscience.
Karumbaiah L, Saxena T, Bellamkonda RV. World Scientific Publishing. 1:351-363, 2014 Aug.

Polyamino Acids in Regenerative Medicine and Drug Delivery.
Saxena T, Karumbaiah L, Valmikinathan CM. Natural and Synthetic Biomedical Polymers. n/a, 2014 Mar.

Neural Tissue Engineering.
Karumbaiah L, Bellamkonda RV. Neural Engineering. 765-794, 2013.