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The recent explosion in development of micro/nanotechnologies is increasingly providing opportunities to use devices to investigate and/or aid neurological functionality. Neural interfaces link the nervous system to internal or external devices – creating possibilities for bi-directional information exchange, (and its correction), between different areas of the nervous system (normally through a device) – thereby recording, stimulating, restoring or supplementing neurological functionality. For example, Brain Computer Interfacing (BCI) is a promising technology that can potentially help return lost motor and sensory function to individuals suffering from debilitating injuries to the nervous system.

A key component of BCIs are intracortical neural interfaces (INIs), which can provide the quality of neural signals required to control an external prosthesis such as a robotic arm. In reality, however, the robust foreign body response and blood-brain barrier breach caused by indwelling neural interfaces causes degradation of signal quality, and chronic device failure: material and structural incompatible with brain tissue, make INIs incapable of functioning chronically. Our work in this field aims at designing neurointegrative intracortical neural interfacing systems, and to develop non-invasive implantation strategies, to help reduce the foreign body response to the indwelling INIs and consequential chronic failure.