The Translational GlycoMaterials Lab also offers research opportunities to undergraduate students who are motivated to learn more about regenerative bioscience, traumatic brain injury or biomaterial development. Our students get hands on training to preform brain surgeries on rats and we work closely with the University of Georgia's Center for Undergraduate Research Opportunities. We also participate in national REU programs for visiting student researchers.
Translational Glycomaterials and Neural Repair Lab
University of Georgia, Regenerative Bioscience Center
Injuries and diseases of the central nervous system have limited treatment options, resulting in devastating long-term consequences for individuals who suffer from them. Research in the Translational Glycomaterials and Neural Repair Lab is focused on investigating brain extracellular matrix adaptations in injury and disease and devising novel and clinically translatable strategies to promote endogenous repair and prevent disease progression.
#1 Glycomaterials Design and Development
#2 Traumatic Brain Injuries (TBI)
#3 Brain Tumors
#4 Alzheimer’s Disease and Related Dementias
Glioblastoma (GBM) is the most commonly occurring brain tumor in adults. It carries a devastating prognosis, with the majority of patients rarely surviving beyond 12-15 months post-diagnosis and treatment. There are no effective treatments and the current standard of care has not changed over the past two decades. We are interested in understanding mechanisms by which brain tumors adapt and alter their microenvironment in order to spread and evade therapeutic targeting. In doing so, we hope to uncover novel therapeutic targets and develop more effective treatments to improve patient survival.
Over 2.5 million people sustain traumatic brain injuries (TBIs) every year. These can span a wide range of severities from mild, moderate, to severe injuries. Individuals who sustain a TBI experience lifelong disabilities and are at a high risk of developing Alzheimer’s Disease (AD) and AD related dementias (ADRD). There are currently no effective treatments for TBI. We are developing novel therapeutic strategies that are aimed at protecting brain tissue and accelerating endogenous repair and refunctionalization of brain circuitry after TBI. These approaches address the urgent and unmet clinical need for effective therapeutics across all TBI severities.