Publications

Selected Publications ( see complete list on Google Scholar )

• Serafini, C. E., Davarzani, A., Cappabianca, D., Li, Z., Baez Collazos, D., Mamaghani, D., ... & Robles, F. E. (2026). Longitudinal, label-free, high-resolution imaging of glioblastoma spheroid response to therapy: a translational tool for preclinical evaluation of chemotherapy, radiation, and immunotherapy. Optica, 13(2), 211-226. https://doi.org/10.1364/OPTICA.574860

• Tang, R., Latchoumane, C. F., Chopra, A., Sarkar, M., Kim, C., Gonsalves, N., ... & Karumbaiah, L. (2025). A 3D Human Neuron-on-Chip Platform to Monitor Neuronal Injury Responses. bioRxiv, 2025-08. https://doi.org/10.1101/2025.08.06.667201

• Sarkar, M. M., Gonsalves, N., Davarzani, A., Mitchell, E., Singh, A. M., Karumbaiah, L., & Stice, S. L. (2025). Disrupting Akt-Wnt/β-catenin signaling suppresses glioblastoma stem cell growth and tumor progression in immunocompetent mice. bioRxiv, 2025-07. https://doi.org/10.1101/2025.07.25.666376

• Serafini, C., Davarzani, A., Cappabianca, D., Li, Z., Collazos, D.B., Mamaghani, D., Mao, L., Saha, K., Karumbaiah, L. and Robles, F., 2025. (preprint). Longitudinal and continuous label-free monitoring of glioblastoma patient-derived tumor spheroid treatment response using quantitative oblique back illumination microscopy.​ https://www.researchsquare.com/article/rs-6529836/v1

• Serafini, C.E., Davarzani, A., Cappabianca, D., Collazos, D.B., Li, Z., Mamaghani, D., Tommasi, A., Sarko, L., Denne, N.L.V., Mao, L. and Saha, K., 2025, March. Three-dimensional quantitative phase imaging for the evaluation of glioblastoma targeting CAR T-cell efficacy. In Quantitative Phase Imaging XI (Vol. 13329, pp. 16-26). SPIE. https://doi.org/10.1117/12.3039313

• Lizana-Vasquez, G., Ramasubramanian, S., Davarzani, A., Cappabianca, D., Saha, K., Karumbaiah, L. and Torres-Lugo, M. (2024), In Vitro Assessment of Thermo-Responsive Scaffold as a 3D Synthetic Matrix for CAR-T Potency Testing Against Glioblastoma Spheroids. J Biomed Mater Res. https://doi.org/10.1002/jbm.a.37823

• Filan, C., Davarzani, A., Cappabianca, D., Tommasi, A., Sarko, L., Denne, N. L. V., ... & Robles, F. E. (2024, April). Three-dimensional Quantitative Phase Imaging for the Assessment of Glioblastoma Multiforme Treatment Efficacy in Human Spheroids. In Microscopy Histopathology and Analytics (pp. MM5A-4). Optica Publishing Group. https://doi.org/10.1364/MICROSCOPY.2024.MM5A.4

• Gonsalves, N., Sun, M. K., Chopra, P., Latchoumane, C. F., Bajwa, S., Tang, R., ... & Karumbaiah, L. (2024). Neuritogenic glycosaminoglycan hydrogels promote functional recovery after severe traumatic brain injury. Journal of Neural Engineering. https://doi.org/10.1088/1741-2552/ad5108

• Filan, C. E., Bharadwaj, S., Costa, P. C., Davarzani, A., Mao, L., Karumbaiah, L., & Robles, F. E. (2024, March). Tracking cellular and subcellular dynamics with quantitative oblique back-illumination microscopy. In Quantitative Phase Imaging X (Vol. 12852, pp. 51-58). SPIE. https://doi.org/10.1117/12.3000091

• ​Logun, M., Colonna, M. B., Mueller, K. P., Ventarapragada, D., Rodier, R., Tondepu, C., ... & Karumbaiah, L. (2023). Label-free in vitro assays predict the potency of anti-disialoganglioside chimeric antigen receptor T-cell products. Cytotherapy. https://doi.org/10.1016/j.jcyt.2023.01.008

• Forghani, R., Goodnight, B., Latchoumane, C. F. V., & Karumbaiah, L. (2023). AutoRG: An Automatized Reach-to-Grasp Platform Technology for Assessing Forelimb Motor Function, Neural Circuit Activation, and Cognition in Rodents. Journal of Neuroscience Methods, 109798. https://doi.org/10.1016/j.jneumeth.2023.109798​​

• McCrary, M. R., Jiang, M. Q., Jesson, K., Gu, X., Logun, M. T., Wu, A., ... & Wei, L. (2022). Glycosaminoglycan scaffolding and neural progenitor cell transplantation promotes regenerative immunomodulation in the mouse ischemic brain. Experimental Neurology, 357, 114177. https://doi.org/10.1016/j.expneurol.2022.114177

• ​Latchoumane, C. F. V., Chopra, P., Sun, L., Ahmed, A., Palmieri, F., Wu, H. F., ... & Karumbaiah, L. (2022). Synthetic Heparan Sulfate Hydrogels Regulate Neurotrophic Factor Signaling and Neuronal Network Activity. ACS applied materials & interfaces, 14(25), 28476-28488.

• ​Chvatal, S. A., Logun, M. T., Sullivan, D. D., Hayes, H. B., Millard, D., Katie, M. P., ... & Karumbaiah, L. (2022). GD2 CAR-T cells engineered using retroviral transduction or CRISPR editing exhibit strong cytolytic potency against glioma stem cells. Cancer Research, 82(12_Supplement), 2817-2817.

• Sun, M. K., Kaimal, A., Latchoumane, C. F. V., Forghani, R., Lenear, C. E., Holmes, P. V., ... & Karumbaiah, L. (2022). Prenatal Exposure to Diethylhexyl Phthalate Impairs the Recovery of Spatial Memory Post-traumatic Brain Injury in a Sex-specific Manner.

• Tondepu, C., & Karumbaiah, L. (2022). Glycomaterials to investigate the functional role of aberrant glycosylation in glioblastoma. Advanced Healthcare Materials, 11(4), 2101956.

• Latchoumane, C. F. V., Forghani, R., & Karumbaiah, L. (2021). Cortical Laminar Recording of Multi-unit Response to Distal Forelimb Electrical Stimulation in Rats. Bio-protocol, 11(22), e4153-e4153.

• Hayes, H. B., Logun, M. T., Chvatal, S. A., Mueller, K., Piscopo, N., Das, A., ... & Karumbaiah, L. (2021). Kinetics and potency of T cell and CAR-T cell mediated cytolysis of glioma stem cells. Cancer Research, 81(13_Supplement), 1552-1552.

• Latchoumane, C. F. V., Betancur, M. I., Simchick, G. A., Sun, M. K., Forghani, R., Lenear, C. E., ... & Karumbaiah, L. (2021). Engineered glycomaterial implants orchestrate large-scale functional repair of brain tissue chronically after severe traumatic brain injury. Science Advances, 7(10), eabe0207.

• Latchoumane, C. F. V., Barany, D. A., Karumbaiah, L., & Singh, T. (2020). Neurostimulation and reach-to-grasp function recovery following acquired brain injury: Insight from pre-clinical rodent models and human applications. Frontiers in Neurology, 11, 835.

• Latchoumane, C. F. V., Betancur, M. I., Simchick, G. A., Sun, M. K., Forghani, R., Lenear, C. E., ... & Karumbaiah, L. (2020). Neurotrophic Factor-Laden Acellular Chondroitin Sulfate Scaffolds Promote Chronic Functional Recovery After Severe Traumatic Brain Injury. bioRxiv, 2020-06.

• Sun, M. K., Passaro, A. P., Latchoumane, C. F., Spellicy, S. E., Bowler, M., Goeden, M., ... & Karumbaiah, L. (2020). Extracellular vesicles mediate neuroprotection and functional recovery after traumatic brain injury. Journal of neurotrauma, 37(11), 1358-1369.

• McCrary, M. R., Jesson, K., Wei, Z. Z., Logun, M., Lenear, C., Tan, S., ... & Wei, L. (2020). Cortical Transplantation of Brain‐Mimetic Glycosaminoglycan Scaffolds and Neural Progenitor Cells Promotes Vascular Regeneration and Functional Recovery after Ischemic Stroke in Mice. Advanced healthcare materials, 9(5), 1900285.​

• Lyon, J.G., Karumbaiah, L., Bellamkonda, R.V. (2020). Neural Tissue Engineering. In: He, B. (eds) Neural Engineering. Springer, Cham. https://doi.org/10.1007/978-3-030-43395-6_22

• Liu, Y., Zhao, W., Cheng, R., Logun, M., del Mar Zayas-Viera, M., Karumbaiah, L., & Mao, L. (2020). Label-free ferrohydrodynamic separation of exosome-like nanoparticles. Lab on a Chip, 20(17), 3187-3201.

• Logun, M. T., Wynens, K. E., Simchick, G., Zhao, W., Mao, L., Zhao, Q., ... & Karumbaiah, L. (2019). Surfen-mediated blockade of extratumoral chondroitin sulfate glycosaminoglycans inhibits glioblastoma invasion. The FASEB journal, 33(11), 11973.